Cancer Gene Idetified-But Guess What, Being Fit and Healthy Helps (Personal TrainerAnyone?)
From BBC online news:
Scientists have unlocked the entire genetic code of two of the most common cancers – skin and lung – a move they say could revolutionise cancer care. Not only will the cancer maps pave the way for blood tests to spot tumours far earlier, they will also yield new drug targets, say the Wellcome Trust team. Scientists around the globe are now working to catalogue all the genes that go wrong in many types of human cancer. The UK is looking at breast cancer, Japan at liver and India at mouth. China is studying stomach cancer, and the US is looking at cancers of the brain, ovary and pancreas.
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The International Cancer Genome Consortium scientists from the 10 countries involved say it will take them at least five years and many hundreds of thousands of dollars to complete this mammoth task. But once they have done this, patients will reap the benefits.Professor Michael Stratton, who is the UK lead, said: “These catalogues are going to change the way we think about individual cancers.
“By identifying all the cancer genes we will be able to develop new drugs that target the specific mutated genes and work out which patients will benefit from these novel treatments.
“We can envisage a time when following the removal of a cancer cataloguing it will become routine.”It could even be possible to develop MoT-style blood tests for healthy adults that can check for tell-tale DNA patterns suggestive of cancer.
Russian roulette-The scientists found the DNA code for a skin cancer called melanoma contained more than 30,000 errors almost entirely caused by too much sun exposure.
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The lung cancer DNA code had more than 23,000 errors largely triggered by cigarette smoke exposure. From this, the experts estimate a typical smoker acquires one new mutation for every 15 cigarettes they smoke. Although many of these mutations will be harmless, some will trigger cancer. Wellcome Trust researcher Dr Peter Campbell, who conducted this research, published in the journal Nature, said: “It’s like playing Russian roulette. Most of the time the mutations will land in innocent parts of the genome, but some will hit the right targets for cancer.” By quitting smoking, people could reduce their cancer risk back down to “normal” with time, he said. The suspicion is lung cells containing mutations are eventually replaced with new ones free of genetic errors. By studying the cancer catalogues in detail, the scientists say it should be possible to find exactly which lifestyle and environmental factors trigger different tumours.
So the key message here is that the healthier we are the less chance we have of getting a deadly cancer, even if we are genetically predisposed to it. Stopping smoking can seem like a very daunting task, but it CAN be easy, I know this because I’ve done it! Picture this, I am a personal trainer in Windsor and Maidenhead, and after every client, whether I’m running with them, doing circuits, or resistance training, I need a cigarette after each session. I have one first thing in the morning, in the shower, would you believe. But then I was recommended the”easy Way to Stop Smoking” by Allen Carr. This book changed my like, plus the life of my partner, her sister, and ger mother, who all stopped with little difficulty after reading this book or going to the lecture. So give it a go, you have everything to gain and nothing to lose!





